发明名称 |
Certain 2,6-diisopropyl-4-(4-fluoro-phenyl)-3,5-bis-dimethyl-3',5'-dihydroxy-hept-6-enoate-pyridine derivatives useful for treating lipoproteinaemia and arteriosclerosis |
摘要 |
For the treatment of lipoproteinaemia and arteriosclerosis, the new disubstituted pyridines of the formula <IMAGE> (I) in which R1 is optionally substituted aryl or heteroaryl, R2 is cycloalkyl or optionally substituted alkyl, R3 is hydrogen, cycloalkyl, or optionally substituted alkyl, aryl or heteroaryl, X is -CH2-CH2- or -CH=CH-, A is <IMAGE> R6 is hydrogen or alkyl, and R7 is hydrogen, alkyl, aralkyl or a cation.
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申请公布号 |
US4968689(A) |
申请公布日期 |
1990.11.06 |
申请号 |
US19890298453 |
申请日期 |
1989.01.17 |
申请人 |
BAYER AKTIENGESELLSCHAFT |
发明人 |
ANGERBAUER, ROLF;FEY, PETER;HUEBSCH, WALTER;PHILIPPS, THOMAS;BISCHOFF, HILMAR;PETZINNA, DIETER;SCHMIDT, DELF;GUENTER, THOMAS |
分类号 |
C07D333/24;A61K31/44;A61K31/4418;A61K31/443;A61K31/4433;A61P3/00;A61P9/00;A61P9/10;C07C69/738;C07C229/32;C07C255/14;C07D213/30;C07D213/48;C07D213/54;C07D213/55;C07D213/80;C07D307/54;C07D401/04;C07D401/14;C07D405/04;C07D405/06;C07D405/14;C07D409/04;C07D409/14;C07D413/04;C07D413/14;C07D417/04;C07D417/14 |
主分类号 |
C07D333/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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