发明名称 NOVEL PEPTIDE AND ANTI-FUNGUS AGENT THEREFROM
摘要 NEW MATERIAL:A peptide of the formula ((1) and (2), and (3) and (4) are directly bound. respectively; Arg-NH2 represents that the carboxyl group of Arg has been substituted by amide group) and its salt. USE:Anti-fungus agents for medical use, preservatives, antibiotics and preservatives for coating. Virtually non-toxic. PREPARATION:Firstly, a tris hydrochloric acid buffer containing both NaCl and benzamidine hydrochloride is added to the blood cells of horseshoe crab of Malaysia origin followed by grinding and centrifugation treatment. Thence, dil HCl is added to the resultant precipitate followed by grinding and centrifugation to obtain a supernatant. Finally, the supernatant is put to column chromatography treatment.
申请公布号 JPH02270897(A) 申请公布日期 1990.11.05
申请号 JP19890089830 申请日期 1989.04.11
申请人 TAIYO FISHERY CO LTD 发明人 NAKAJIMA HIROSHI;TSUBOI ISAMI;KITAGAWA TAKASHI;KIMURA SEIJI
分类号 A61K38/00;A01N37/46;A61P31/04;C07K1/20;C07K7/08;C07K14/435 主分类号 A61K38/00
代理机构 代理人
主权项
地址