发明名称 |
PHARMACEUTICAL COMPOSITIONS |
摘要 |
Pharmaceutically active agents are formulated with a bile salt and at least one additional component of bile. The bile salt and additional component may be provided as a naturally occurring bile mix, such as a methanolic extract of animal (for example, ox) bile. A lymphatic absorption promoter such as oleic acid or glycerol mono-oleate may also be present. Pharmaceuticals formulated in this way can benefit from enhanced bioavailability, particularly as hepatic first-pass metabolism is reduced. NSAIDs and cardiovascular agents are particularly suitable for formulation by means of the invention. |
申请公布号 |
WO9012583(A1) |
申请公布日期 |
1990.11.01 |
申请号 |
WO1990GB00605 |
申请日期 |
1990.04.20 |
申请人 |
CORTECS LIMITED |
发明人 |
STORY, MICHAEL, JOHN;BARNWELL, STEPHEN, JOHN |
分类号 |
A61K35/413;A61K47/28;A61K47/46 |
主分类号 |
A61K35/413 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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