摘要 |
A hydrophilic substitute of a bicontinuous cubic phase in equilibrium is polymerized and unpolymerized components are subsequently removed and replaced with water, creating a hydrogel which is locally highly cross-linked but of high water content because of the presence of a periodic network of water-filled macropores superposed on the hydrogel matrix. The diameter of these macropores can be preselected between 20 Angstroms and several hundred Angstroms or even higher, and in general will be much larger than micropores within the hydrogel. The hydrogel has high water content, good mechanical integrity and notch strength and high permeability to oxygen. Pore size can be chosen to allow passage of molecules of pre-selected size. The hydrogel is useful in a contact lens and other biological and medical applications. |