发明名称 |
NEW 6- OR 7-METHYLENANDROSTA-1, 4-DIENE-3,17-DIONE DERIVATIVES AND PROCESS FOR THEIR PREPARATION |
摘要 |
<p>The invention relates to new 6- or 7-methylenandrosta-1,4-diene-3,17-diones of the following formula <CHEM> wherein R is hydrogen or fluorine; R1 is hydrogen or C1-C6 alkyl; R2 is hydrogen or halogen; one of R3 and R4 is =CH2 and the other is hydrogen or C1-C4 alkyl, and when R3 is =CH2, at least one of R and R4 is other than hydrogen; and the symbol @ @@ represents a double bond and the symbol @@@ represents a single bond when R3 is =CH2 or the symbol @@@ represents a single bond and the symbol @@@ represents a double bond when R4 is =CH2, which are useful in therapy, in particular as anti-cancer agents.</p> |
申请公布号 |
GR3000085(T3) |
申请公布日期 |
1990.10.31 |
申请号 |
GR19890400089T |
申请日期 |
1989.06.29 |
申请人 |
FARMITALIA CARLO ERBA S.R.L. |
发明人 |
BUZZETTI, FRANCO;BARBUGIAN, NATALE;LOMBARDI, PAOLO;DI SALLE, ENRICO |
分类号 |
A61K31/565;A61P35/00;C07J1/00;C07J21/00;C07J71/00;(IPC1-7):C07J1/00 |
主分类号 |
A61K31/565 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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