发明名称 |
2,4-DIPHENYL-1,3-DIOXANE. |
摘要 |
The invention provides a novel group of 4(Z)-([2,4,5-cis]-2,4-diphenyl-1,3-dioxan-5-yl)hexenoic acids of formula I, wherein X is F, Cl, Br, CF3, CN, CH3O or NO2 and one of Y and Z is hydrogen or fluoro and the other is hydrogen, and their pharmaceutically acceptable salts; together with their pharmaceutical compositions for use in treating a variety of disease conditions. Also provided are methods for the manufacture of novel compounds. Representative compounds are those in which X is 2-cyano or 2-chloro and Y and Z are both hydrogen. |
申请公布号 |
DE3674240(D1) |
申请公布日期 |
1990.10.25 |
申请号 |
DE19863674240 |
申请日期 |
1986.05.09 |
申请人 |
IMPERIAL CHEMICAL INDUSTRIES PLC, LONDON, GB |
发明人 |
BREWSTER, ANDREW GEORGE, BOLLINGTON MACCLESFIELD CHESHIRE, GB;BROWN, GEORGE ROBERT, WILMSLOW CHESHIRE, GB;SMITHERS, MICHAEL JAMES, MACCLESFIELD CHESHIRE, GB |
分类号 |
A61K31/335;A61K31/357;A61P7/02;A61P9/08;A61P9/10;C07D319/06;(IPC1-7):C07D319/06 |
主分类号 |
A61K31/335 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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