New retro-inverse, one- or more bond bearing analogues of thymopentin, a method for synthesizing the same and their employment for the preparation of pharmaceutical.

摘要

New thymopentin (TP5) analogues are disclosed which contain in their peptide chain one or more retro-inverse bonds. The new compounds have one of the following general formulas (I), (II) and (III) <CHEM> <CHEM> wherein R is hydrogen or an acyl radical, and R<1> is a group of the formula -OR<2> wherein R<2> is a hydrogen atom or a hydrocarbon radical, and the corresponding acid or basic addition salts pharmaceutically acceptable. Such new compounds have immunostimulating activity.