摘要 |
<p>A pharmaceutical composition (preferably in reconstitutable form) comprising loperamide or a pharmaceutically acceptable salt or pro-drug thereof (e.g. its hydrochloride acid addition salt) and an oral rehydration agent such as a sugar, an oral rehydration salt, or an amino acid (especially a mixture of glucose, one or more chloride salts, and a bicarbonate or a citrate salt) in admixture or conjunction with a pharmaceutically acceptable carrier or excipient is useful in the treatment of diarrhoea. The loperamide may be used in 0.5 to 10 mg per unit dose, and the oral rehydration agent in 0.1 to 10 g per unit dose.</p> |