| 发明名称 |
UREA BASED LIPOXYGENASE INHIBITING COMPOUNDS |
| 摘要 |
Substituted phenyl, naphthyl, and thienyl N-hydroxy urea compounds form a class of potent inhibitors of 5- and 12-lipoxygenase and are thus useful compounds in the treatment of inflammatory disease states where leukotrienes and other products of lipoxygenase enzyme activity are implicated. |
| 申请公布号 |
WO9012008(A1) |
申请公布日期 |
1990.10.18 |
| 申请号 |
WO1990US01488 |
申请日期 |
1990.03.20 |
| 申请人 |
ABBOTT LABORATORIES |
发明人 |
BROOKS, DEE, W.;STEWART, ANDREW, O.;SUMMERS, JAMES, B.;KERKMAN, DANIEL, J.;MARTIN, JONATHAN, G. |
| 分类号 |
C12N9/99;A61K31/17;A61K31/195;A61K31/22;A61K31/275;A61K31/38;A61K31/381;A61P29/00;A61P37/00;A61P37/08;A61P43/00;C07C275/64;C07C323/44;C07C323/47;C07C335/40;C07D333/20;C07D333/22;C07D333/28;C07D333/32;C07D333/36;C07D335/08;C07D409/04;C07D409/06;C07D409/12 |
主分类号 |
C12N9/99 |
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