发明名称 |
GALENICAL FORM CONTAINING NIFEDIPINE, AND PROCESS FOR ITS PREPARATION |
摘要 |
1. Nifedipine-containing hard gelatine capsule, characterized in that the nifedipine is present in molecular dispersion as a solidified melt in a mixture of polyethylene glycols which are liquid and semi-solid at room temperature or polyethylene glycols which are liquid and solid at room temperature or polyethylene glycols which are liquid, semi-solid and solid at room temperature, the ratio of liquid to non-liquid polyethylene glycols being from 7:23 to 23:7, the solidification point of the mixture being between 25 degrees C and 62 degrees C and the mixture having viscosities of 0.1 to 18,000 Pas (1 to 180,000 poise) measured on a mixture of up to 40% by weight of water and polyethylene glycol mixtures at 20 degrees C.
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申请公布号 |
EP0182007(B1) |
申请公布日期 |
1990.10.17 |
申请号 |
EP19850109688 |
申请日期 |
1985.08.01 |
申请人 |
DR. RENTSCHLER ARZNEIMITTEL GMBH & CO. |
发明人 |
KOEHNE, HANS, DR. DIPL.-CHEM.;LAHR, WOLFGANG;SCHMERSAHL, UWE HEIN, DR. |
分类号 |
A61K31/455;A61K9/14;A61K9/48;A61K31/44;A61K47/00;A61K47/30;A61P9/08;A61P9/10;A61P9/12 |
主分类号 |
A61K31/455 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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