发明名称 |
MONOCLONAL ANTIBODIES AND HYBRIDOMA CELLS, PROCESS FOR PREPARING THEM AND THEIR USE |
摘要 |
<p>The invention relates to novel monoclonal antibodies having a high affinity for human renin, derivatives thereof, processes for the preparation of these antibodies and their derivatives, hybridoma cell lines that produce these antibodies, and to processes for the preparation of said hybridoma cells lines. The monoclonal antibodies according to the invention and their derivatives can be used for the qualitative and quantitative determination of human renin and structurally similar renin, for the purification of human renin and structurally similar renin and for the treatment of high blood pressure and cardiac insufficiency.</p> |
申请公布号 |
EP0158599(B1) |
申请公布日期 |
1990.10.10 |
申请号 |
EP19850810152 |
申请日期 |
1985.04.03 |
申请人 |
CIBA-GEIGY AG |
发明人 |
HEUSSER, CHRISTOPH, DR.;ANDREATTA, RUDOLF HEINRICH, DR.;ALKAN, SEFIK, PROF. DR.;WOOD, JEANETTE, DR. |
分类号 |
G01N33/573;A61K38/00;A61K39/00;A61K39/395;A61P9/12;C07K14/005;C07K14/195;C07K14/81;C07K16/00;C07K16/40;C07K19/00;C12N5/10;C12N9/64;C12N15/02;C12P21/00;C12P21/08;C12R1/91;G01N33/577 |
主分类号 |
G01N33/573 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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