摘要 |
<p>This invention provides a group of hydroxycycloalkanephenoxyethylamine antidepressant derivatives of the following structural formula: in which R1 is hydrogen or alkyl of 1 to 6 carbon atoms; R2 is alkyl of 1 to 6 carbon atoms; R3 and R4 are, independently, hydrogen, hydroxyl, alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, alkanoyloxy of 2 to 7 carbon atoms, halo or trifluoromethyl; R5 is hydrogen, alkyl of 1 to 6 carbon atoms or alkanoyl of 2 to 7 carbon atoms; and n is one of the integers 0, 1, 2 or 3; or a pharmaceutically acceptable salt thereof.</p> |