摘要 |
PCT No. PCT/GB90/00345 Sec. 371 Date Oct. 24, 1991 Sec. 102(e) Date Oct. 24, 1991 PCT Filed Mar. 7, 1990 PCT Pub. No. WO90/10702 PCT Pub. Date Sep. 20, 1990.A recombinant thermophilic NAD-dependent dehydrogenase having a hydrophobic amino acid at position 104 and/or 102. The enzymes are effective in catalysing the dehydrogenation of homologues of pyruvic acid of formula CnH2n+1COCOOH, wherein n is>1, to homologues of lactic acid of formula CHnH2n+1CHOHCOOH, wherein n is>1. |