RADIATION/MICROBE BIOASSAY

摘要

A bioassay method and apparatus for rapidly detecting and measuring the toxic response of bacteria to chemicals whose levels are too low to produce acute toxic symptoms, but from which a toxic response or damage might develop years following chronic exposure. The bacteria used are Bacillus subtilis isogenic strains subjected to chemical exposure and illuminated by radiation such as a laser beam. Detectors detect differential light scattered by the bacteria, and a response index of cytotoxicity and genotoxicity is calculated.