| 摘要 |
1-Acyl-2-pyrazoline derivs. (II) are produced by cyclising by heating acylhydrazone derivs. (I) where R1= H, pyridyl, pyrazinyl, alkyl acyl (phenyl or phenyl substd. by lower alkyl) a halogen atom(s) or alkoxy; R2, R3 and R4= (independently) H, furyl, pyridyl, alkyl or acyl. Acylhydrazones (I) are easier to synthesise and more stable than an alternative starting material, 2-pyrazoline derivs., which are reacted with an acid chloride or anhydride to produce cpds. (II). Cpds. (II) are drugs for the treatment of cerebral edema.
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