发明名称 ATSUKABENOCHUKUMAKUROKYUKEIRYUSHISEIZOHOHOOYOBISONOSOCHI
摘要 A process and apparatus are provided for making hollow macrospherical particles. The particles themselves are particularly adapted for use as anti-perspirants. The particles have a diameter between about 10 and 74 microns, preferably predominating between 15 and 44 microns, and a greater than unit density. As such, they are not subject to deep lung penetration. The process for producing the particles comprises providing a solution containing the materials from which the particles are made, diffusing the solution through small pores by centrifugal force such that the resulting hollow particles have a diameter greater than the pore diameter, and drying the solution droplets in a stream of heated air. The apparatus for producing the macrospherical particles comprises a centrifugal atomizer having a porous sintered metal filter ring which is rotated inside a spray drying chamber. The filter is treated to produce hollow macrospheres having substantially smooth outer walls of such thickness that they can withstand normal shipment and handling without significant fragmentation.
申请公布号 JPH0244808(B2) 申请公布日期 1990.10.05
申请号 JP19870080877 申请日期 1987.04.01
申请人 ARMOUR PHARMA 发明人 JEEMUSU EFU KOJISHETSUKU
分类号 A61K33/06;A61J3/02;A61K8/00;A61K8/11;A61K8/26;A61K8/28;A61K8/34;A61K9/16;A61Q15/00;B01D1/18;B01J2/02;B01J2/04;B05B3/10;B29B9/00;C08J3/12 主分类号 A61K33/06
代理机构 代理人
主权项
地址