发明名称 Orally administrable ibuprofen compositions.
摘要 <p>The invention concerns a taste neutral aqueous base ibuprofen composition suitable for oral administration which comprises suspending containing about 0.8% to about 4% weight ibuprofen by volume of the total composition comprising a primary suspension stabilizing combination of ingredients and a primary taste masking combination of ingredients, the suspension stabilizing combination of ingredients comprising about 0.1% to about 2% weight suspension stabilizing combination by volume of the total composition, the taste masking combination comprising about 20% to about 70% weight taste masking combination by volume of the total composition, the composition also containing one or more buffer acids in an amount sufficient to adjust the pH to about 1.5 up to about 3.5 and to provide a buffer capacity within the range of 0.03 to 0.05 between the initial pH and a pH which is 1.0 pH unit higher than the initial pH, and water qs to 100% by volume of the composition.</p>
申请公布号 EP0390369(A2) 申请公布日期 1990.10.03
申请号 EP19900302750 申请日期 1990.03.15
申请人 AMERICAN HOME PRODUCTS CORPORATION 发明人 MOTOLA, SOLOMON;MOGAVERO, ANNABELLE;AGISIM, GARY ROBERT;PANOPOULOS, PAMELA N.
分类号 A61K9/00;A61K9/10;A61K9/107;A61K31/19;A61K47/10;A61K47/26 主分类号 A61K9/00
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