| 摘要 |
NEW MATERIAL:The compound of formula I [R1 is H, OH or lower alkanoyl; R2 is H or lower alkyl; x is -CONH-, -COO-, -OCO- or -COH=C(OH)-; n is 1 or 2]. EXAMPLE:4-[3,5-Bis(trimethylsilyl)phenylcarboxamide]benzoic acid. USE:A differentiation inducing substance for cancer cell, especially leukemia cell. A remedy for psoriasis. A remedy for immunological disease and inflammatory disease. PREPARATION:A compound of formula I wherein X is -CONH- can be produced by converting a benzoic acid derivative of formula n to its reactive derivative (acid halide, mixed acid anhydride, etc.), condensing the compound with p- aminobenzoic acid or its ester derivative and optionally hydrolyzing the resultant compound. |
