摘要 |
alpha -Aminoalkylphosphonic and alpha -aminoalkylphosphinic acids of the formula I <IMAGE> (I) where n=1 or 0, R1=H, CH3 or CH2-C6H5 R2=H (for n=1) and also=alkyl or phenyl (for n=0) are prepared by Hofmann deradation from compounds of the formula II <IMAGE> (II) wherein n and R1 have the same meaning as in formula I, R3=alkyl (for n=1), alkyl or phenyl (for n=0), and Mp+=p-valent cation, with subsequent working up in the known manner. Some of the compounds I are biologically active, and some are intermediates for the preparation of biologically active compounds.
|