ELECTRICAL TRANSDERMAL DRUG APPLICATOR SYSTEM

摘要

A transdermal drug applicator for passing at least one drug for delivery to the systemic circulation system of a patient through the skin. The applicator includes a drug applicator containing a colloidal suspension having at least one drug for delivery to the body of a patient, the colloidal suspension comprising a fluid medium and generally large, as compared to the size of molecules, particles in the fluid medium. The particles and the medium are of different permittivities. The drug reservoir is capable of being placed in electrical contact with the skin of the patient. A voltage device imposes electrostatic field lines upon the fluid medium so as to create a non-uniform electrostatic field in the fluid medium when the drug reservoir is placed on the skin. The particles migrate in accordance with the principle of dielectrophoresis so as to pass through the skin into the systemic circulation system.