摘要 |
Phenylnaphthyridines functionalised in position 3, of formula: <IMAGE> in which: X and Y denote the hydrogen atom, a halogen, a lower alkyl group containing 1 to 5 carbon atoms, trifluoromethyl, an alkoxy, methylthio, nitro or cyano and may be in an ortho, meta or para position in the aromatic ring, preferably in a meta or para position Z is a functional group which may contain: - an unsaturation - an alkylthio functional group substituted or otherwise by guanidine, urea or nitrodiaminoethene derivatives - an alkylsulphinyl functional group - an ether functional group - an alcohol functional group, esterified or otherwise - a ketone functional group - an acidic functional group, esterified or otherwise - a halogen - a cyano functional group - an amine functional group - an aminoacid or amidoacid functional group - a phosphorylated functional group - an aromatic or heteroaromatic nucleus and medications containing one of these derivatives or optionally one of their nontoxic addition salts with acids. |