ANTHELMINTIC BIOCONVERSION PRODUCTS

摘要

5/DLR13 17737 TITLE OF THE INVENTION ANTHELMINTIC BIOCONVERSION PRODUCTS There are disclosed new compounds with significant antiparasitic activity which are prepared by fermenting the compounds paraherquamide or dihydroparaherquamide in a novel microorganism identified as Cunninghamella blakesleeana MF-4415. The paraherquamide compound is modified by the microorganism by ring hydroxylation or ketonization. The compounds are significant antiparasitic and anthelmintic agents and compositions for that use are also disclosed.