A new human gene termed MCC is disclosed. Methods and kits are provided for assessing mutations of the MCC gene in human tissues and body samples. Gross rearrangement and point mutations in MCC are observed in human tumor cells. MCC is expressed in most normal tissues. These results suggest that MCC is a tumor suppressor.
申请公布号
WO9216656(A1)
申请公布日期
1992.10.01
申请号
WO1992US00377
申请日期
1992.01.16
申请人
THE JOHNS HOPKINS UNIVERSITY;THE UNIVERSITY OF UTAH;THE CANCER INSTITUTE, JAPANESE FOUNDATION FOR CANC