发明名称 ISOQUINOLINE DERIVATIVES FOR THE TREATMENT OF GLAUCOMA OR OCULAR HYPERTENSION
摘要 The use of isoquinoline derivatives for the treatment of glaucoma or ocular hypertension. The isoquinoline derivatives are of formula I wherein R1 is a hydrogen atom or a C1-C6 alkyl group and R2 is a C1-C6 alkyl group. The stability of the isoquinoline derivatives when used in the form of a solution is improved by incorporating therein compounds having a phenolic hydroxyl group and/or glycols serving as a stabilizer.
申请公布号 CA2013167(A1) 申请公布日期 1990.09.28
申请号 CA19902013167 申请日期 1990.03.27
申请人 TADOKORO, TOYOHIRO;SATO, KIYOSHI;HATAKEYAMA, SHIGEKI;KAWASE, SHIGEO;UENO, MASAO 发明人 TADOKORO, TOYOHIRO;SATO, KIYOSHI;HATAKEYAMA, SHIGEKI;KAWASE, SHIGEO;UENO, MASAO
分类号 A61K31/47;(IPC1-7):C07D217/24 主分类号 A61K31/47
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