| 摘要 |
Synthetically modified avermectin derivatives are disclosed containing novel alkyl, and alkenyl substituents at position 25 and having additional substituents at positions 4 min - and 4 sec - of the oleandrose structural part. The compounds are prepared from the known C-25 substituted avermectin derivatives by the appropriate chemical reactions at the 4 min -, and 4 sec -positions. The new compounds are potent antiparasitic agents, in particular, the compounds are anthelmintic, insecticidal and acaricidal agents. |
