发明名称 AGENTS CONTAINING IMIDAZOLINE DERIVATIVES FOR SYSTEMIC COMBATING OF ECTOPARASITES IN HOST ANIMALS AND NOVEL IMIDAZOLINE DERIVATIVES
摘要 The present invention relates to agents for systemic combating of ectoperasites in host animals, containing a compound of the formul I <IMAGE> (I) in which R1 denotes hydrogen, (C1-C5)-alkyl, (C1-C3)-halogenoalkyl or halogen; R2 and R3 independently of one another denote (c1-C5)-alkyl, (C2-C5)-alkenyl, (C2-C5)-alkynyl, (C3-C7)-cycloalkyl, (C3-C7)-cycloalkenyl, (C1-C3)-halogenoalkyl, halogen, cyano, nitro, (C1-C5)-alkoxy, (C1 -C3)-alkoxy-C1-C3)-alkyl, (C1-C3)-halogenoalkoxy or (C1-C3)-alkylthio, or R2 and R3 together form a polymethylene chain having 2 to 5 carbon atoms: R4 denotes hydrogen, (c1-C10)-alkyl, (C2-C5)-alkenyl or (C3-C7)-cycloalkyl; R5 denotes hydrogen, (C1-C10)-alkyl, (C3-C5)-alkenyl, C3-C5)-alkynyl, (C3-C7)- cycloalkyl, (C3-C7)-cycloalkenyl, (C1-C3)-halogenoalkyl or (C1-C3)-alkoxy-(C hd 1-C3)-alkyl; X denotes oxygen, sulfur or an -NR6-group; and R6 denotes hydrogen, (C1-C5)-alkyl, (C3-C5)-alkenyl, C3-C5)-alkynyl, (C3-C7)-cycloalkyl, C3-C7)-cycloalkenyl, (C1-C3)-halogenoalkyl or (C1-C3)-alkoxy-(C1 -C3)-alkyl, or biologically tolerated acid addition salts thereof. The compounds of the formulas I are novel in some cases and are likewise included in the invention.
申请公布号 ZA8909722(B) 申请公布日期 1990.09.26
申请号 ZA19890009722 申请日期 1989.12.19
申请人 HOECHST AKTIENGESELLSCHAFT 发明人 HERBERT STARK;GERHARD SALBECK;WERNER BONIN
分类号 A61K31/415;A61P33/00;C07D233/20;C07D233/22;C07D233/24 主分类号 A61K31/415
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