发明名称 |
Method of inhibiting osmotic water flow |
摘要 |
This invention provides a method of inhibiting osmotic water flow across mammalian cell membranes which involves contacting the water channels of the cell membranes with an effective amount of a glucose transport blocker or of digitonin so as to inhibit osmotic water flow across the membranes. Additionally, this invention provides a method of treating a subject afflicted with a condition associated with abnormal osmotic water flow across cell membranes which comprises administering to the subject an effective amount of a glucose transport blocker or of digitonin so as to contact the water channels of the subject's cell membranes and inhibit osmotic water flow across the membranes.
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申请公布号 |
US4959355(A) |
申请公布日期 |
1990.09.25 |
申请号 |
US19870025959 |
申请日期 |
1987.03.16 |
申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK |
发明人 |
FISCHBARG, JORGE;LIEBOVITCH, LARRY S.;KONIAREK, JAN P. |
分类号 |
A61K31/05;A61K31/12;A61K31/305;A61K31/40;A61K31/70 |
主分类号 |
A61K31/05 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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