发明名称 MONOCLONAL ANTIBODY FOR USE IN DETECTION AND TREATMENT OF CHILDHOOD LEUKEMIA
摘要 The subject invention pertains to a novel cell line and the monoclonal antibody produced by the cell line. Advantageously, the novel monoclonal antibody binds specifically with the acute lymphocytic leukemia antigen. Thus, this antibody can be used in the detection of childhood leukemia as well as in therapeutic procedures such as bone marrow purging. The novel monoclonal antibody can also be used to construct hybrid toxin proteins which can selectively seek out and eliminate target cells.
申请公布号 WO9010692(A1) 申请公布日期 1990.09.20
申请号 WO1990US01392 申请日期 1990.03.14
申请人 UNIVERSITY OF FLORIDA 发明人 CASSANO, WILLIAM, F.
分类号 A61K35/28;A61K38/00;A61K47/48;C07K16/30;C12N5/20;C12P21/08;G01N33/574 主分类号 A61K35/28
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