摘要 |
<p>A process for providing a biological pacemaker for the human heart wherein the sino-atrial (S-A) node cells (12) are removed from the heart and cultured to generate a critical mass of S-A node cells of sufficient quantity to generate a depolarization wave capable of stimulating the cells of the myocardium to ensure normal or near-normal pumping action in the heart. The critical mass of S-A node cells are then implanted in the myocardial tissue of the right ventricle (19) to provide biological pacing for the heart which is sensitive to and variable with normal increase and decrease of output demands on the heart.</p> |