发明名称 PYRIMIDINE TYPE MEVALONOLACTONES
摘要 <p>A compound of formula (I), wherein R?1 and R2¿ are independently hydrogen, alkyl, cycloalkyl, alkoxy, n-butoxy, i-butoxy, sec-butoxy, R5R6N- (wherein R?5 and R6¿ are independently hydrogen or alkyl), trifluoromethyl, trifluoromethoxy, difluoromethoxy, fluoro, chloro, bromo, phenyl, phenoxy, benzyloxy, hydroxy, trimethylsilyloxy, diphenyl-t-butylsilyloxy, hydroxymethyl or -O(CH¿2)lOR?15 (wherein R15 is hydrogen or alkyl, and l is 1, 2, or 3); or when located at the ortho position to each other, R?1 and R2¿ together optionally form -CH=CH-CH=CH- or methylene dioxy; Y is -CH¿2?-, -CH2CH2-, -CH=CH-, -CH2CH=CH- or -CH=CH-CH2-; Z is -Q-CH2WCH2-CO2R?12¿, (a), (b) or (c), wherein Q is -C(O)-, -C(OR¿13?)2- or -CH(OH)-; W is -C(O)-, -C(OR13)2-, -C(R11)(OH)-.</p>
申请公布号 WO1990010624(A1) 申请公布日期 1990.09.20
申请号 JP1989000250 申请日期 1989.03.08
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