发明名称 |
Mutants of urinary plasminogen activator, their production and use. |
摘要 |
<p>Mutants of urinary plasminogen activator are described having alone or in combination a change of the glycosylation pattern, truncation of the N-terminus, and modification of the cleavage site. These polypeptides are produced by expression of mutated genes created by site directed mutagenesis.</p> |
申请公布号 |
EP0387380(A1) |
申请公布日期 |
1990.09.19 |
申请号 |
EP19890104762 |
申请日期 |
1989.03.17 |
申请人 |
BEHRINGWERKE AKTIENGESELLSCHAFT |
发明人 |
PAQUES, ERIC PAUL, DR. |
分类号 |
A61K38/00;C07K14/00;C12N1/21;C12N9/72;C12N15/58;C12R1/91 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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