发明名称 |
IMPROVED METHOD FOR PRODUCING FACTOR VIII:C-TYPE PROTEINS |
摘要 |
An improved method for producing Factor VIII:c-type proteins is disclosed which involves culturing mammalian cells which are capable of expressing the protein. In accordance with this invention the cells are cultured in a medium containing an effective amount of a substance comprising (a) von Willebrand Factor-type protein, (b) a phospholipid or phospholipid mixture, or a mixture of (a) and (b). |
申请公布号 |
EP0362218(A4) |
申请公布日期 |
1990.09.19 |
申请号 |
EP19880903710 |
申请日期 |
1988.04.06 |
申请人 |
GENETICS INSTITUTE, INC. |
发明人 |
KAUFMAN, RANDAL, J.;ADAMSON, S., ROBERT |
分类号 |
C12N15/09;A61K38/00;C07K14/755;C12N15/12;C12P21/02;C12R1/91 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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