| 摘要 |
<p>THERAPEUTIC COMPOUNDS Compound for use in a method for treatment of the human or animal body by therapy, characterised in that the compound is a carboxy azetidine derivative of the general formula I or a pharmaceutically acceptable salt, ester, amide, alkylamide, hydrazide or alkylhydrazide thereof: I in which: X represents one or the groups CH2, CHR or CR2; Y represents one of the groups CHR, CR2 or CH.CO2H and Z represents one of the groups CH2, CHR, CR2 or CH.CHO2H; the or each R independently represents an alkyl, alkenyl or cycloalkyl group or an aryl or aralkyl group optionally substituted on the aryl nucleus by one or more of the same or different substituents selected from halogen atoms, alkyl groups and alkoxy groups; and one but only one of Y and Z must represent a CH.CO2H group. Therapeutic compositions containing such compounds are also described as are packs containing such compositions together with instructions for use in a method of treatment by therapy.</p> |
