| 发明名称 |
Cholesteryl modified oligonucleotides |
| 摘要 |
Oligonucleotides modified at their backbones by the attachment of cholesteryl are described. The modified oligonucleotides anchor in the cell membrane to serve as a probe and to provide therapeutic activity.
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| 申请公布号 |
US4958013(A) |
申请公布日期 |
1990.09.18 |
| 申请号 |
US19890362200 |
申请日期 |
1989.06.06 |
| 申请人 |
NORTHWESTERN UNIVERSITY |
发明人 |
LETSINGER, ROBERT L. |
| 分类号 |
A61K31/704;A61K31/7088;A61P31/12;A61P31/18;C07H21/00;C07J43/00;C07J51/00 |
主分类号 |
A61K31/704 |
| 代理机构 |
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代理人 |
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| 地址 |
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