发明名称 |
BIOLOGISK AKTIVT MATERIALE KARAKTERISERET VED KATABOLISK AKTIVITET, ALMENT ASSOCIERET MED CACHEXIA-INDUCERENDE TUMORER, PRAEPARATER, PRODUKTION OG ANVENDELSE DERAF |
摘要 |
A biologically active lipolytic factor having an average molecular weight substantially less than 5000 daltons and comprising active molecular species having molecular weights of about 3000 daltons, 1500 daltons and 700-800 daltons is disclosed. The factor can be isolated, using chromatographic methods, from cachexia-inducing tumours, cultures of tissue cells of cachexia-inducing tumours especially cultures of a MAC16 tumour cell line, or from body fluids such as serum or urine of mammals bearing cachexia-inducing tumours. Cancer diagnostic applications in relation to human individuals are described as well as uses for screening and identifying potential anti-cachetic and/or antitumour therapeutic agents. |
申请公布号 |
DK222790(D0) |
申请公布日期 |
1990.09.17 |
申请号 |
DK19900002227 |
申请日期 |
1990.09.17 |
申请人 |
CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED |
发明人 |
TISDALE, MICHAEL JOHN;BECK, SUSAN ANNE |
分类号 |
A61K38/00;A61K35/12;A61K35/16;A61K35/22;A61K39/395;A61P3/04;A61P35/00;C07K14/435;C07K16/00;C07K16/18;C07K16/30;C12P21/00;C12P21/08;C12R1/91;G01N33/53;G01N33/574;G01N33/577;(IPC1-7):C12N9/20;C07K15/28 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|