发明名称 PHARMACEUTICAL PREPARATION SUITABLE FOR TOPICAL APPLICATION
摘要 PURPOSE: To obtain the subject preparation, comprising a fibroblast growth factor and hyaluronic acid (salt) and having good and quick healing effects on wounds at the time of healing the wounds even in the case of insufficiently healed wounds. CONSTITUTION: This pharmaceutical preparation comprises (A) a fibroblast growth factor which is a group of basic or acidic polypeptides acting as a mitogen for an endothelial cell and (B) hyaluronic acid and/or its physiologically permissible salt (preferably an Na salt). The amounts of the ingredients are 10<-5> to 1wt.%, preferably 10<-4> to 10<-3> wt.% ingredient A and 0.05-5wt.%, preferably 0.2-2wt.% ingredient B. The resultant pharmaceutical preparation can be used to treat wounds injured by capillary functions in which normal healing is especially interrupted (e.g. diabetic angiopathy, burn injury or ulcer after thrombosis).
申请公布号 JPH02231429(A) 申请公布日期 1990.09.13
申请号 JP19900000154 申请日期 1990.01.05
申请人 MERCK PATENT GMBH 发明人 FURANTSU DORENKU
分类号 A61K38/00;A61K38/18;A61P17/00;A61P43/00 主分类号 A61K38/00
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