Apparatus and methods for performing electrofusion at specific anatomical sites

摘要

Electrofusion of biological particles to specific areas of tissue is accomplished in vivo through the use of electrode members that conform to the configuration and dimension of the tissue at the electrofusion site. The electrode members are positioned in close physical proximity to one another so that when an electrical potential difference is established between them, current flow is limited to the area of tissue between the electrodes so that tissue remote from the selected electrofusion site is substantially unaffected by such current flow. A general apparatus and method is supplemented with two illustrative apparatus and methods for accomplishing in vivo electrofusion on corneas and in cervical areas.