发明名称 |
DIASTEREOISOMER A OF 2,6-DIMETHYL-4-(3-NITROPHENYL)-1, 4-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID 3- (1-BENZYLPYRROLIDIN-3-YL) ESTER 5-METHYL ESTER AND DEXTROROTATORY ISOMER THEREOF |
摘要 |
<p>This invention relates to diastereoisomer A of 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-(1-benzylpyrrolidin-3-yl)ester 5-methyl ester, dextro-rotatory optical isomer thereof, and the pharmaceutically acceptable acid addition salts thereof. The invention further relates to a process of producing these compounds and also to medicaments using these compounds as an effective component. The compounds of this invention have a vasodilating activity and a hypotensive activity.</p> |
申请公布号 |
CA1273930(A) |
申请公布日期 |
1990.09.11 |
申请号 |
CA19850479294 |
申请日期 |
1985.04.16 |
申请人 |
YAMANOUCHI PHARMACEUTICAL CO., LTD. |
发明人 |
TAMAZAWA, KAZUHARU;KOJIMA, TADAO;ARIMA, HIDEKI;MURAKAMI, YUKIYASU;ISOMURA, YASUO;OKADA, MINORU;TAKANOBU, KIYOSHI;TAKENAKA, TOICHI |
分类号 |
A61K31/44;C07B57/00;C07D207/24;C07D211/90;C07D401/12;C07D405/00;(IPC1-7):C07D401/12 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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