| 摘要 |
PURPOSE:To efficiently obtain the subject compound having drug effects, such as antitussive or anti-inflammatory action, by extracting a licorice (Glycyrrhiza glabra var. glandulifera) with supercritical carbon dioxide containing a specific mixture coexisting as an entrainer therein. CONSTITUTION:An entrainer prepared by preferably mixing methanol with an organic amine at (2:1)-(3:1) ratio in an amount of 5-20vol% coexists in a gas of supercritical carbon dioxide and the resultant gas, together with a licorice, is placed in a supercritical gas extraction separator and extracted at 40 deg.C under 400kg/cm<2> pressure for 1-4hr to separate and purify the above-mentioned extracted essence. Thereby, the objective glycyrrhizin is obtained. |
