摘要 |
<p>A high performance affinity chromatography separation device comprising: A) a chromatographic column containing: b) a packing material, wherein the packing material is a plurality of non-porous, monodisperse polymeric particles having i) a particle size in the range of 0.01 to about 5 micrometers and ii) surface reactive groups which are directly or indirectly reactive with free amino groups, sulfhydryl groups, carboxy groups or aldehyde groups of biological ligands is disclosed.</p> |