| 摘要 |
<p>Compounds that are analogs of etoposide and exhibit antitumor activity are disclosed. The compounds of the present invention have formula (I), where R1 is β-OCH2CH2NH2, β-NHCH(CH3)CH2OH, β-NHCH2CH(CH3)OH, β-Cl, β-Br, β-OH, α-OH, β-NH2, α-NH2, β-NHCH2CH2OH, α-NHCH2CH2OH, β-NHCH2CH2CH3, β-NHCH2CH2OCH3, β-NHCH2CH=CH2, β-NHCH2CH(OH)CH3, β-NHCH2CH2CH2OH, β-OCH2CH2OH, (a), (b), (c), (d), (e), (f), (g), (h), (i), (j), (k), (l), (m), (n), (o), (p), (q), (r), (s), (t), (u), (v) or (w). R2 is H, or Br; R3 is H, or Br; R4 is H, or Br; R5 is H, or Br; and R6 is H, or -CH3.</p> |
