| 摘要 |
<p>The present invention relates to novel 2-picolylamine derivatives of general formula I. <CHEM> wherein R1 represents an alkyl or phenylalkyl radical; R2 is hydrogen , C1-C4 acyl or C1-C4 alkoxycarbonyl; R3 is either an electron pair, in which case t means nothing and q is 0, or R3 is hydrogen or C1-C4, in which case t is (+) and q=1; Z is oxygen or an aminocarboniloxy group; X is O or S; m and n are 2-6; p is O-3; A- is a pharmaceutically acceptable ion. These compounds are PAF antagonists and, consequently, useful in the treatment of the diseases in which this substance is involved.</p> |
