| 摘要 |
Compounds of formula (II), wherein each of R and R<4> is independently H, C1-C6 alkyl, benzyl or an alternative biolabile ester-forming group; R<2> is a C4 alkyl group; R<3> is H, OH, C1-C4 alkyl or C1-C4 alkoxy; and R<5> is defined to include a range of alkyl, alkenyl, alkynyl, arylalkynyl, cycloalkyl, cycloalkenyl, alkoxy, amino, substituted amino, amido, sulphonamido and substituted alkyl groups; and phamaceutically acceptable salts thereof, are diuretic agents of utility in the treatment of hypertension, heart failure, renal insufficiency and other disorders. |
