GENE Any-RF, DORMANCY REGULATORY SUBSTANCE, PROCESS FOR PRODUCING THE SAME AND CELL REGULATOR FOR VITAL CELLS

摘要

The present invention provides a gene Any-RF derived from an insect, having dormancy-control activity and biological cell-control function; a dormancy-control substance and a method for preparing the same; as well as a biological cell-control agent, which comprises, as an effective component, a physiologically active substance having a biological cell-control function and which never causes any antigen-antibody reaction in the living body. The gene encodes for a protein having an amino acid sequence specified as Sequence No. 1 in SEQUENCE LISTING: Asp-Ile-Leu-Arg-Gly, whose C-terminal is amidated and having a molecular weight of 570.959. The physiologically active substance comprising such a gene is a peptide, which can be isolated and purified by adding an acid-methanol aqueous solution to Antheraea yamamai, triturating the resulting mixture, centrifuging the same and then treating the resulting supernatant in an HPLC system. The peptide permits the control of the dormancy of insects and is also useful as a biological cell-control agent, which comprises, as an effective component, such a peptide.