| 发明名称 |
IL-2 ANALOGS CONTAINING N-LINKED GLYCOSYLATION SITES |
| 摘要 |
36 Title BT-0023 IL-2 Analogs Containing N-linked Glycosylation Sites Biologically active analogs of human IL2, which differ from natural IL2 by the substitution of amino acid residues to form N-linked glycosylation sites in the molecule, are prepared by recombinant DNA techniques. Such analogs of IL2 are N-linked glycosylated when expressed in eukaryotic cells. Natural IL2 is not N-linked glycosylated. 36
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| 申请公布号 |
CA2011095(A1) |
申请公布日期 |
1990.08.31 |
| 申请号 |
CA19902011095 |
申请日期 |
1990.02.28 |
| 申请人 |
DU PONT (E. I.) DE NEMOURS AND COMPANY |
发明人 |
MITCHELL, KENNETH F.;VALLONE, CAROL A. |
| 分类号 |
C12N15/09;A61K38/00;C07K14/435;C07K14/52;C07K14/55;C07K19/00;C12N15/26;C12P21/02;C12R1/19;C12R1/91;(IPC1-7):C12N15/26 |
主分类号 |
C12N15/09 |
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