发明名称 |
Method and apparatus for maldi analysis |
摘要 |
Matrix assisted laser desorption/ionization (MALDI) is performed in a manner that thermalizes large analyte ions in a plume of desorbed material for spectroscopic analysis. The thermalized ions have a low or zero mean velocity and are presented at a well-defined instant in time, reducing artifacts and sharpening the spectral peaks. In one embodiment the light is delivered to a matrix or sample holder having a cover, baffle or compartment. The baffle or compartment impedes or contains a plume of desorbed material and the analyte undergoes collisions to lower its mean velocity and directionality. Thus "thermalized" the analyte ions are passed to a mass analysis instrument.
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申请公布号 |
US2002109085(A1) |
申请公布日期 |
2002.08.15 |
申请号 |
US20020117558 |
申请日期 |
2002.04.03 |
申请人 |
HILLENKAMP FRANZ;LOUGH DAVID M.;HIGGINS G. SCOTT;REUTER DIRK |
发明人 |
HILLENKAMP FRANZ;LOUGH DAVID M.;HIGGINS G. SCOTT;REUTER DIRK |
分类号 |
G01N27/62;B01D59/44;C40B60/14;G01N27/64;H01J49/00;H01J49/04;H01J49/10;H01J49/16;(IPC1-7):H01J49/04 |
主分类号 |
G01N27/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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