PEPTIDE LACTONE AND DERIVATIVES THEREOF, A PROCESS FOR THE PREPARATION THEREOF AND MEANS FOR CARRYING OUT THE PROCESS

摘要

Peptide lactone and derivatives thereof, a process for the preparation thereof and means for carrying out the process The substance hormaomycin and compounds obtainable therefrom by lactonecleavage and optionally subsequent esterification with a lower alkanol are described. Hormaomycin is obtainable by fermentation with the strain Streptomyces griseoflavus DSM 5195 and exhibits with respect to the strains Arthrobacter crystallopoietes ATCC 15481 and Arthrobacter oxydans ATCC 14358 a minimum inhibiting concentration of less than 0.001 .mu.g/ml. Hormaomycin can be used as a medicament and for stimulating aerial mycelium formation in Streptomycetes and probably has the structure shown in formula I. (I)