摘要 |
Compound of formula: <IMAGE> in which: - R1 represents: . a 1,2,3,6-tetrahydro-1-pyridyl radical substituted at position 4 with a 3-indolyl or phenyl radical or a phenyl radical substituted with a halogen atom or a hydroxyl or methoxy radical, . a 1-piperazinyl radical substituted at position 4 with a 2-pyridyl, 1,2-benzisothiazol-3-yl, 1,2-benzisoxazol-3-yl or phenyl radical or a phenyl radical substituted with a methoxy, alkyl, hydroxyl or nitro radical or a halogen atom, . a piperidino radical substituted at position 4 with a 4-fluorobenzoyl, bis(4-fluorophenyl)methylene or 2-oxo-1-benzimidazolinyl radical, one or two phenyl radicals or a phenyl radical substituted with a halogen atom, - either: . R2 and R3, which are identical, represent a hydrogen, chlorine or bromine atom and R4 represents a hydrogen atom, or . R2 and R4 represent a hydrogen atom and R3 represents a chlorine or bromine atom, or . R2 and R3 represent a hydrogen atom and R4 represents a chlorine or bromine atom . and R5 represents a =CH- group, - or R2, R3 and R4 represent a hydrogen atom and R5 represents a nitrogen atom, - and either: . R6 represents an alkyl radical and R7 and R8 represent a hydrogen atom, or else . R7 represents an alkyl radical, alkoxy, hydroxyl, dialkylamino, piperidino, morpholino or thiomorpholino and R6 and R8 represent a hydrogen atom, or else . R6 and R7 represent a hydrogen atom and R8 represents an alkyl radical. Processes for manufacturing them and medicinal products containing them.
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