Methods for conjugating peptides are provided comprising i) reacting a peptide with a first compound comprising a functional group in the presence of a transglutaminase capa-ble of incorporating said compound into the peptide to form a transaminated peptide, and ii) reacting said transaminiated peptide with e.g. a functionalised polymer capable of reacting with the functional group incorporated in the peptide in the enzymatic reaction.
申请公布号
WO2005070468(A2)
申请公布日期
2005.08.04
申请号
WO2005DK00028
申请日期
2005.01.18
申请人
NOVO NORDISK A/S;JOHANSEN, NILS, LANGELAND;ZUNDEL, MAGALI;DOERWALD, FLORENCIO, ZARAGOZA