发明名称 PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME
摘要 Phenylpyridazine compounds represented by the following formula (I): <CHEM> (wherein R1 represents a substituted or unsubstituted phenyl or a a substituted or unsubstituted pyridyl; R2 represents a lower alkoxy group, a lower alkylthio group, a lower alkylsufinyl group or a lower alkylsulfonyl group; R3 represents a hydrogen atom or a lower alkoxy group; and R4 represents a hydrogen atom or a substituted alkyl group), are provided having excellent inhibitory activity against interleukin-1 beta production, and useful in the treatment of prevention of diseases caused by stimulation of interleukin-1 beta production, such as immune system diseases, inflammatory diseases, and ischemic diseases.
申请公布号 KR100777623(B1) 申请公布日期 2007.11.27
申请号 KR20027016860 申请日期 2001.07.06
申请人 发明人
分类号 C07D237/10;A61K31/50;A61P9/10;A61P19/10;A61P29/00;C07D237/08;C07D237/12;C07D237/14;C07D237/18;C07D237/20;C07D237/24;C07D401/12;C07D405/04;C07D417/04 主分类号 C07D237/10
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